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Creatine Monophosphate

Phosphocreatine is a chemical form of energy stored primarily in muscle tissues used primarily for muscle contraction during the anaerobic phases. Phosphocreatine is a compound of creatine and phosphoric acid, Mol.Wt. 211, which forms readily and naturally within the body, being made from three amino acids: arginine, glycine, and methionine. It is the equivalent of ATP (adenosine triphosphate), the energy molecule of the body, and acts to provide energy for the contraction of muscle tissues. The end product of phosphocreatine metabolism is creatinine, and is excreted in the urine.

Creatinine is often used as an index of kidney function since a kidney malfunction will sometimes show decreased creatinine excretion rates. The reaction occurs thusly: Creatine + ATP = Creatine phosphate + ADP, catalyzed by CPK (creatine phosphokinase). Creatine (monophosphate) is used by body builders to increase muscle mass, and is one of the few substances which will actually increase muscle mass without exercise, although quite large amounts are needed ( upwards of 5 grams+ per day) for it to have any effect after loading 20 grams per day for the first week.

Phosphocreatine reportedly can help in the process of recuperation of the body after injury or surgery as well as decrease both triglycerides and LDL cholesterol, however there are other nutraceuticals which can provide the same if not better response without having to consume the large amounts of this ingredient by itself. In an average meat diet, we naturally consume about a gram of phosphocreatine per day, and around 100-150 grams is generally stored within the body.

 


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