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Creatine Monophosphate
Phosphocreatine is a chemical
form of energy stored primarily in muscle tissues used primarily
for muscle contraction during the anaerobic phases. Phosphocreatine
is a compound of creatine and phosphoric acid, Mol.Wt. 211,
which forms readily and naturally within the body, being made
from three amino acids: arginine, glycine, and methionine. It
is the equivalent of ATP (adenosine triphosphate), the energy
molecule of the body, and acts to provide energy for the contraction
of muscle tissues. The end product of phosphocreatine metabolism
is creatinine, and is excreted in the urine.
Creatinine is often used as an index of kidney function since
a kidney malfunction will sometimes show decreased creatinine
excretion rates. The reaction occurs thusly: Creatine + ATP
= Creatine phosphate + ADP, catalyzed by CPK (creatine phosphokinase).
Creatine (monophosphate) is used by body builders to increase
muscle mass, and is one of the few substances which will actually
increase muscle mass without exercise, although quite large
amounts are needed ( upwards of 5 grams+ per day) for it to
have any effect after loading 20 grams per day for the first
week.
Phosphocreatine reportedly can help in the process of recuperation
of the body after injury or surgery as well as decrease both
triglycerides and LDL cholesterol, however there are other nutraceuticals
which can provide the same if not better response without having
to consume the large amounts of this ingredient by itself. In
an average meat diet, we naturally consume about a gram of phosphocreatine
per day, and around 100-150 grams is generally stored within
the body.
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