Sepia officinalis may be used as a Homeopathic or used simply as a micro-nutritional (animal product). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine. Sepia officinalis is the scientific name of Cuttlefish ink.

As a Homeopathic or used simply as a micro-nutritional, Sepia officinalis has demonstrated effectiveness against the following symptomology: indifferent to those loved best; averse to occupation, to family; irritable, easily offended; very sad; -pelvic organs relaxed; bearing down sensations as if everything would escape through the vulva; -menses too late and scanty, irregular; early and profuse, sharp clutching pains; -violent stitches upward in the vagina, from uterus to umbilicus; -prolapse of uterus and vagina; -vagina painful especially upon coition; -hot flashes at menopause with weakness and perspiration; -feels cold even in a warm room; -one of the most important uterine remedies (Boericke); tobacco dyspepsia; -irritable, easily offended; very sad; anxious toward evening; -abuse of tobacco (Boericke).