Santoninum is used as Homeopathic medicine (alkaloid). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine.

As a Homeopathic or used simply as a micro-nutritional, Santoninum has demonstrated effectiveness against the following symptomology: hyperemic conditions from continuous fine work, as in seamstresses; -also to be remembered in (early) cataract; objects look yellow (Dewey) -"[Santoninum] has been reported to be highly serviceable in choroiditis and atrophy of the optic nerve and in amblyopia..." (Blackwood)