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Radix glycyrrhizae (Licorice, DGL, DGL Extract, Gl)
Licorice, also known as Radix
glycyrrhizae, is native to the Mediterranean region and parts
of Asia, and is cultivated worldwide. It was introduced to the
Greeks by the Scythians; Theophrastus recommended the roots
for dry coughs and pectoral diseases. The plant was named from
the Greek 'glukos' (sweet) and 'riza' (a root) by Dioscorides.
The past forms have been corruptions of this: Glycyrrhiza>Liquiritia>Licorys.
The root's medical use is recorded in England in 1264, in Germany
in the 11th century and 1450, and in the 15th century in Italy.
Licorice (Radix glycyrrhizae) has been use as an immune stimulant
for over 3,000 years. Licorice contains many natural chemicals,
one of which is glycyrrhizine, a cortisone substitute used in
Egypt without the associated withdrawal syndrome. Licorice appears
to aid in the body's self-repair mechanisms. Much folklore about
the properties of this herb have been written, from bone and
joint problems, upset stomach, to a highly effective laxative,
and most recently scientific investigation has revealed a basis
for much of it "herbapeutic" powers.
Italian scientists (1979-80) first noted the antiviral activities
imparted or induced by Licorice root (Radix glycyrrhizae) such
as the extracellular destruction of virus particles. The prevention
of intracellular "uncoating," or activation, of infecting viruses
and the impairment of the assembling ability of virus structural
components has been shown to be the result of licorice application.
Extract of licorice has been most effective against viral hepatitis.Recently,
Chinese scientists discovered that phytomedicinals in licorice
root actually activate the interferon mechanism within the body,
an essential part of the Immune System. Japanese scientists
also demonstrated that Licorice root proved to be effective
against highly resistive staphylococcus aureus, strains of bacteria
which had previously proved resistent to penicillin and streptomycin
as well as succeeding drug resistent generations of that strain.
Still other studies have well documented the antiinflammatory
effects and corticosteroid-like activity of Licorice root, or
the phytomedicinal, glycyrrhetinic acid and its derivatives
found in Licorice root. Radix glycyrrhizae is also a traditional
Chinese herb, which acts to aid the body's cleansing processes
in discharging the waste it filters so that the body's natural
filtering system may function more efficiently.
In China, herbalists say that this particular herb helps maintain
the Chi or "life energy" in man, the electro- magnetic pathways
of the body. When such balance is achieved, the body's defenses
are held in check and the stimulation or the overproduction
of free "intruders" is avoided, lessening if not circumventing
the difficulties of allergic-like responses to waste products
not properly discharged. Hence, Radix glycyrrhizae is thought
to be useful in the control of runny and stuffed-up noses, itching
eyes, and related problems. It is also useful in eliminating
catarrh of the upper respiratory tract and gastric/duodenal
ulcers.Active ingredients include coumarine, flavonoids, glycyrrhetic
acid, phytosterols, potassium or calcium salts.
According to controlled clinical studies, glycyrrhizic acid
and the aglycone of glycyrrhizic acid accelerate the healing
of gastric ulcers. Secretolytic and expectorant effects have
been confirmed in tests on rabbits. In the isolated rabbit ileum,
an antispasmodic action has been observed at concentrations
of 1:2500 to 1:5000. When glycrrhetinic acid (one of the active
ingredients in licorice) is removed from the extract, DGL remains
which is particularly effective against duodenal ulcers. GA
is useful against disease, though, and can enhance immune system
function, but it can also cause some water retention which is
not always wanted such as when treating an ulcer. However, adding
a few drops of licorice to water was associated with a lower
level of experimentally-induce skin cancers when compared to
a control group who drank ordinary water. (Nutrition and Cancer,
vol. 15, 3 & 4, 1991.) Using large amounts (+5g/day) of licorice
can increase blood pressure.Topically, licorice is an antiinflammatory
and can be used for psoriasis and eczema. Incidentally, most
licorice-flavored candy in the U.S. gets its flavor from anise,
not licorice, so eating so-called licorice candy will not give
one the "licorice benefit"!
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