Osmium metallicum may be used as a Homeopathic or used simply as a micro-nutritional (metal). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine.

As a Homeopathic or used simply as a micro-nutritional, Osmium metallicum has demonstrated effectiveness against the following symptomology and problems of the eyes: veins of fundus large and tortuous; profuse lachrymation; -sharp pain in orbit; lids spasmodically closed with sharp orbital pain; -halo around candle flame, rainbow, bluish-green or yellow; at a distance candle flame seems enveloped by dust or smoke; dim sight; letters run together, as from a fog; -one of the prominent remedies for glaucoma, which it has actually cured (Moffat).