Natrum muriaticum is used as a Homeopathic medicine (mineral; tissue salt). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine.

As a Homeopathic or used simply as a micro-nutritional, Natrum muriaticum has demonstrated effectiveness against the following symptomology: "Attack begins in the morning in bed, diminishing after rising and moderate exercise, but becomes worse from rapid motion, and is accompanied by nausea and vomiting of transparent phlegm (mucous) or water; dull, heavy headache with drowsiness and profusion of tears, sleep not refreshing; headache before, during and after menses; pain as if head would burst, made worse from c oughing (may go on to loss of consciousness; twitching of limbs). " - also for worms. (Lilienthal)

Also, as a Homeopathic or used simply as a micro-nutritional, Natrum muriaticum has demonstrated effectiveness against the following depressive symptomology: "The patient requiring this remedy is melancholic, hypochondriacal, sad, hopeless about the future, easily angered-in fact, consolation aggravates...patient sheds floods of tears ...with this remedy there is a persistent recalling of past unpleasantness and grievances...the patient for whom Natrum muriaticum is suitable is also apt to have unjustifiable antipathy against certain people." (Dewey).