Hepar sulphuris calcaream may be used as a Homeopathic or used simply as a micro-nutritional (mineral). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine.

As a Homeopathic or used simply as a micro-nutritional, Hepar sulphuris calcaream has demonstrated effectiveness against the following symptomology: ill-effects due to arsenic exposure; -ill-effects from abuse of cod-liver oil; -ill-effects from abuse of iodides; -ill-effects from abuse of iron preparations; - (homeopathic) antidote to effects of anesthetic vapors; -ill-effects due to mercury exposure (Boericke)