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GABA (Gamma-aminobutyric acid)
GABA (g-aminobutyric acid), one
of the major inhibitory Amino Acid neurotransmitters of the
central nervous system, is known to be an active a1- & a2-adrenergic
antagonist, helping the body to relax the smooth muscle of arteries
and veins. It acts via the GABA-A and GABA-B cell receptors
to prevent neuronal depolarization and firing of an action potential
occurring in muscles, stopping the muscle from contracting.
An action potential is a rapid, transient, self-propagating
electrical excitation of the membrane of electrically excitable
cells, also known as a spike or nerve impulse (in neurons).
Action potentials occur in nerve, muscle, and neuroendocrine
cells and are generated and propagated through the actions of
voltage-gated ion channels. An action potential is essentially
a brief (approx. 1 ms long), regenerative change in the membrane
potential which occurs in electrically excitable cells such
as the smooth muscle in veins and arteries. Action potentials
are essentially digital signals which encode information as
a temporal sequence. With GABA, G-protein coupled receptor sites
(the largest superfamily of cell-surface receptors) are competed
for in smooth muscle, ensuring that smooth muscle of arteries
and veins relaxes, and that action potentials do not fire. As
the smooth muscle relaxes, arteries and veins begin to vasodilate,
increasing their circumference, allowing more blood to flow
which subsequently reduces blood pressure throughout the circulatory
system.
GABA, a quasi-amino acid, is thought to be one of the most powerful
inhibitory neurotransmitters in the central nervous system operating
as a chemical messenger to its neighbors. GABA is important
in helping the body to naturally regulate nerve function and
enhance the ability of vitamin B3 (niacin) to act. This is an
amino acid which can be derived from yet another amino acid,
glutamic acid. GABA, one of the so called three musketeers (GABA,
Glutamine [GAM] and Glutamic acid [GA]), is believed to be capable
of providing needed nutrition and energy for the brain.GABA
has generally been found to be deficient in clinical and experimental
seizure disorders and is the most widely distributed inhibitory
neurotransmitter in the brain. GABA is helpful in bringing calmness
to the body, promoting tranquility and peace in times of stress
and anxiety. It is also a known precursor to another important
neurotransmitter, gamma-hydroxybutyrate (GHB), which is a natural
sleep inducing compound in the brain, encouraging the body to
produce its own native tryptophan, which in turn is the natural
precursor to the sleep neurotransmitter, serotonin.
GABA is an ingredient in the following product(s):
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BUFFER PH
pH Balancer
Price: $29.95
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| ATTEND STRATEGY PAC
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For Inattentiveness, Memory, and Stress
Price: $81.95
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PARASITIN
Parasite Cleanse
Price: $29.95
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CLEARIN
Acne & Blemishes
Price: $25.95
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