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Bioflavonoid Complex (Bioflavonoids, Flavonoids)

There are more than 4,000 chemically unique flavonoids that have been identified in plants, which only represents a small fraction of that which exists in nature. Unlike the alkaloids which are restricted to about 20% of the flowering plant species, flavonoids occur universally in vascular plant species.

Flavonoids have been used since the 1950's and have demonstrated their abilities to reduce swelling in legs and ankles while strengthening capillaries, reduce allergies and hayfevers since 1960, and since the 1980's we have discovered its antioxidant powers. Flavonoids (along with the carotenoids) provide most of the color compounds found in fruits and vegetables. They are known to be very powerful antioxidants, neutralizing free radicals before they damage cells Flavonoids deter premature aging of skin by binding with collagen fibers, increasing elasticity. Immune-stimulating, antiviral, antiinflammatory, anti-mutagenics, cardio-protective, anti-allergenic, anti-carcinogenic.

Also called polyphenolic flavonoids or polyphenols, Flavonoids, and a special group of them called proanthocyanidins, are found especially in abundance in citrus, green tea extract, bilberry extract and grape seed extracts. Bioflavonoids and some related flavonoids such as herperidin and rutin, and their derivatives, are thought to improve capillary function by reducing abnormal leakage. They have been given to relieve capillary impairment and venous insufficiency of the lower limbs, and for hemorrhoids.

Flavonoids are members of a family of compounds called polyphenols, which means that they have more than one phenol group (Vitamin E tocopherols are monophenolic compounds, having only one phenol group). The greater the number of phenol groups attached to a flavonoid, the greater the versatility it demonstrates within the body, and the more powerful it is as an antioxidant; this is why Flavonoids are generally more powerful than Vitamin E as an antioxidant in water soluble mediums (vitamin E is more powerful in fat soluble mediums, hence both Flavonoids and Vitamin E are needed for optimal health). Flavonoids are found in fruits, vegetables, nuts, seeds, grains and in beverages such as tea, cocoa and wine, being prominent components of citrus fruits and soybeans.

Bioflavonoids are biochemically active flavonoids, having biochemical utility and biological activity. There are two main classes, the anthocyanins and the anthoxanthins. It's now generally recognized that for these to be activated in the body, at least trace amounts of Vitamin C must be present. Flavonoids function as light screens in plants. They actually protect the plant's DNA from UV radiation damage. Flavonoids and vitamin C occur together in plants, and appear to be mutually protective. Flavonoids increase the absorption of vitamin C and influence a large number of enzyme systems, some of which are critically involved in chronic diseases, including cancer.

No other class of biological chemicals seems to exhibit such diverse and numerous nutritional and biochemical actions in mammalian cells. Flavonoids directly affect the Immune system, influencing T-Cell activity, populations of macrophages, smooth muscle cells of the cardiovascular system, neurotransmitter release, lipid perioxidation, cell motility, malignant cell proliferation and more.Until recently, many thought that lower carotenoid intake was associated with higher incidences of lung cancer; however, studies have not clearly demonstrated this relationship. Lately, however, the inverse relationship between flavonoids and risk of lung cancer has been borne out from a report coming from the National Public Health Institute of Finland.

Intakes of flavonoids are relatively low because two important sources (tea and wine) are rarely consumed. The principle source of flavonoids in the Finnish diet (apples) was inversely related to lung cancer risk. [American Journal of Epidemiology, 146(3):223-230, Aug 1997]Pycnogenol, a patented select group of water-soluble Oligomeric Proanthocyanidins (OPC's) in the family of polyphenols produced by Horphag Research, Ltd., has been tested for years because of its powerful blend of simple and complex polyphenols, strengthening capillary function and performing in the body in a myriad of ways, seemingly more powerful than "regular" flavonoids or flavanols. ActiVin, a patented group of proanthocyanidins from InterHealth Company, California, has also proven to be an effective combination of polyphenols, extracted from the seeds of red grapes. See Pycnogenol, ActiVin.

Bioflavonoid Complex is an ingredient in the following product(s):

Ocu-Care




 


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