Atropinum sulphuricum may be used as a Homeopathic or used simply as a micro-nutritional (alkaloid). Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine.

As a Homeopathic or used simply as a micro-nutritional, atropinum sulphuricum has demonstrated effectiveness against the following symptomology: "When glaucoma is chronic in character and the occasional inflammatory exacerbations leave intervals of complete remission we can do a good deal by remedies...Dr. Parenteau tells us that the well known action of atropine in augmenting intraocular tension and aggravating glaucomatous phenomena may be utilized homeopathically by the adoption of the internal administration of the drug in sufficiently attenuated doses." (Hughes)