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Cardiovascular Disease
(CVD) is the leading cause of death in the U.S. and Europe. According
to U.S. 1992 mortality statistics, about one million people per
year die of CVD in the U.S. -that's approximately ½ of all
deaths registered every year, an average of one death every 33
seconds!
CVD includes coronary
heart disease or diseases of the arteries (Atherosclerosis), heart
attack, stroke, high blood pressure, arrhythmia, rheumatic heart
disease and other dysfunctions. In 1994, over 500,000 coronary
bypass surgeries were performed in the U.S. and over 400,000 angioplasties.
These procedures are costly and are often accompanied by prescriptive
drug therapies with unwanted side effects.
Preventing Cardiovascular
Disease with EDTA Chelation
The corrosion of your cardiovascular system is a slow process that
may generally go unnoticed for years. A CVD prevention program should
include improvements to your diet, some daily exercise and nutritional
supplements that will not only improve your overall health but also
"clean out" your veins and arteries through chelation.
Oral chelation "grabs" a number of unwanted substances that
can cause LDL Cholesterol plaque build up and free radical damage
from the cardiovascular system, renders them harmless, and prepares
them for excretion through the urine. Oral Chelation is a natural
process of "roto-rootering" the cardiovascular system,
helping the body cleanse the arteries and veins, as well as detoxify
the liver and kidneys.
EDTA (or ethylenediamine tetra acetic acid, also known as edetic
acid or tetra acetic acid) is a synthetic amino acid having a molecular
weight of 292.25 and a molecule formula of C10H16N2O8
. EDTA is approved by the FDA for the treatment of lead poisoning
and other metal toxicities when used intravenously, and a number
of studies have found it also effective in treating blood vessel
diseases, improving blood flow to the heart, legs and brain. Interestingly,
the U.S. Navy administered EDTA orally to thousands of sailors in
the 1940's to help combat lead toxicity. Today it is also used as
an antioxidant in foods, as a chelating agent in many pharmaceuticals
and cosmeceuticals, and as an anticoagulant for blood taken for
hematological investigations.
EDTA is a
chelating agent (meaning it has the ability to attach itself to
metals and minerals) and forms a stable, soluble complex with
calcium that is readily excreted by the kidneys. In the USA, a
dose of 50 mg per kg body weight of EDTA in 24 hours by slow intravenous
infusion has been suggested for adults with a maximum daily dose
of 3 grams, although dosages up to 5 grams have been used with
complete safety intravenously. EDTA is also used topically for
treatment of calcium deposits, calcified corneal opacities and
burns of the eye. EDTA does not remove the bound calcium in teeth
and bones, only metastatic calcium or pathologic calcium causing
damage to the body.
Oral Assimilation
of EDTA
Assimilation of EDTA is effective when taken either intravenously
or orally. When taken orally, EDTA, like other amino acids of similar
molecular weight, passes through the stomach unaffected where it
is then absorbed directly through the epithelium cells of the duodenum.
EDTA has been incorrectly written about in the past by authors who
apparently have not understood that the biochemistry and assimilation
of proteins (made from chains of amino acids) and unattached Free
Form Amino Acids all occurs in the duodenum, being unaffected by
the stomach and the gastric juices.
Often misunderstood
is the fact that stomach acidity has nothing whatsoever to do
with the digestion of proteins, which all takes place via enzymatic
reaction later in the duodenum, and that orally consumed Free
Form Amino Acids are likewise not affected. In fact, the pH of
the stomach when secreting HCL is generally around 3.0, which
has absolutely no affect on the molecular bonds of Free Form Amino
Acids (including EDTA) and thus, cannot and will not destroy them.
(Please note: EDTA in solution may exhibit a pH of 4.0 all on
its own.)
All Free Form
Amino Acids, including EDTA, need no digestive process to enter
the bloodstream. They are already small enough molecules to enter
the bloodstream immediately; and that's why they are used so effectively
in I.V. parenteral solutions. Thus all Free Form Amino Acids,
including EDTA, will pass unharmed and unchanged into the duodenum
where they then are directly assimilated into the bloodstream.
Again, they are not, as mistakenly alleged by some, broken down
or destroyed by the gastric processes.
Only the liver can change or transaminate one amino acid into
another, and at other times, amino acids can only be broken down
further by the biochemistry within individual cells themselves
for the purpose of energy. But what is important to realize is
that none of these anabolic and degradive processes take place
within the gastrointestinal tract. Thus, the notion that taking
Free Form Amino Acids orally, including EDTA, will not prove effective
in entering the bloodstream is a misnomer. Indeed, as any biochemical
or medical text book will attest, just the opposite is true.
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