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Are There Benefits Behind EDTA Oral Chelation?

The Reasons Behind Oral
EDTA's Effectiveness

page 1 of 2

Cardiovascular Disease (CVD) is the leading cause of death in the U.S. and Europe. According to U.S. 1992 mortality statistics, about one million people per year die of CVD in the U.S. -that's approximately ½ of all deaths registered every year, an average of one death every 33 seconds!

CVD includes coronary heart disease or diseases of the arteries (Atherosclerosis), heart attack, stroke, high blood pressure, arrhythmia, rheumatic heart disease and other dysfunctions. In 1994, over 500,000 coronary bypass surgeries were performed in the U.S. and over 400,000 angioplasties. These procedures are costly and are often accompanied by prescriptive drug therapies with unwanted side effects.

Preventing Cardiovascular Disease with EDTA Chelation
The corrosion of your cardiovascular system is a slow process that may generally go unnoticed for years. A CVD prevention program should include improvements to your diet, some daily exercise and nutritional supplements that will not only improve your overall health but also "clean out" your veins and arteries through chelation.

Oral chelation "grabs" a number of unwanted substances that can cause LDL Cholesterol plaque build up and free radical damage from the cardiovascular system, renders them harmless, and prepares them for excretion through the urine. Oral Chelation is a natural process of "roto-rootering" the cardiovascular system, helping the body cleanse the arteries and veins, as well as detoxify the liver and kidneys.
EDTA (or ethylenediamine tetra acetic acid, also known as edetic acid or tetra acetic acid) is a synthetic amino acid having a molecular weight of 292.25 and a molecule formula of C10H16N2O8 . EDTA is approved by the FDA for the treatment of lead poisoning and other metal toxicities when used intravenously, and a number of studies have found it also effective in treating blood vessel diseases, improving blood flow to the heart, legs and brain. Interestingly, the U.S. Navy administered EDTA orally to thousands of sailors in the 1940's to help combat lead toxicity. Today it is also used as an antioxidant in foods, as a chelating agent in many pharmaceuticals and cosmeceuticals, and as an anticoagulant for blood taken for hematological investigations.

EDTA is a chelating agent (meaning it has the ability to attach itself to metals and minerals) and forms a stable, soluble complex with calcium that is readily excreted by the kidneys. In the USA, a dose of 50 mg per kg body weight of EDTA in 24 hours by slow intravenous infusion has been suggested for adults with a maximum daily dose of 3 grams, although dosages up to 5 grams have been used with complete safety intravenously. EDTA is also used topically for treatment of calcium deposits, calcified corneal opacities and burns of the eye. EDTA does not remove the bound calcium in teeth and bones, only metastatic calcium or pathologic calcium causing damage to the body.

Oral Assimilation of EDTA
Assimilation of EDTA is effective when taken either intravenously or orally. When taken orally, EDTA, like other amino acids of similar molecular weight, passes through the stomach unaffected where it is then absorbed directly through the epithelium cells of the duodenum. EDTA has been incorrectly written about in the past by authors who apparently have not understood that the biochemistry and assimilation of proteins (made from chains of amino acids) and unattached Free Form Amino Acids all occurs in the duodenum, being unaffected by the stomach and the gastric juices.

Often misunderstood is the fact that stomach acidity has nothing whatsoever to do with the digestion of proteins, which all takes place via enzymatic reaction later in the duodenum, and that orally consumed Free Form Amino Acids are likewise not affected. In fact, the pH of the stomach when secreting HCL is generally around 3.0, which has absolutely no affect on the molecular bonds of Free Form Amino Acids (including EDTA) and thus, cannot and will not destroy them. (Please note: EDTA in solution may exhibit a pH of 4.0 all on its own.)

All Free Form Amino Acids, including EDTA, need no digestive process to enter the bloodstream. They are already small enough molecules to enter the bloodstream immediately; and that's why they are used so effectively in I.V. parenteral solutions. Thus all Free Form Amino Acids, including EDTA, will pass unharmed and unchanged into the duodenum where they then are directly assimilated into the bloodstream. Again, they are not, as mistakenly alleged by some, broken down or destroyed by the gastric processes.

Only the liver can change or transaminate one amino acid into another, and at other times, amino acids can only be broken down further by the biochemistry within individual cells themselves for the purpose of energy. But what is important to realize is that none of these anabolic and degradive processes take place within the gastrointestinal tract. Thus, the notion that taking Free Form Amino Acids orally, including EDTA, will not prove effective in entering the bloodstream is a misnomer. Indeed, as any biochemical or medical text book will attest, just the opposite is true.

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