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Systemic Lupus Erythematosus (SLE):
Damaging and Unpredictable

Systemic Lupus Erythematosus is a chronic, inflammatory, disorder of the immune system. In this condition antibodies are made against the person's normal tissue within their body, as a result, Systemic Lupus Erythematosus can be very damaging and unpredictable. This illness usually develops in women during their childbearing years but can manifest in young men, women, and children at anytime. It is more prevalent within Hispanics and African Americans. There is speculation that there genetic predisposition to SLE. The cause of this disease is uncertain, however, Systemic Lupus Erythematosus has been found in a number of patients who have first-degree relatives with lupus. Genetic and environment factors may play a role in the development of this disease.

Systemic lupus Erythematosus can affect many parts of the body, potentially damaging vital organs. This disease can vary in severity among individuals. The condition alternates between flares of symptoms and periods of improvement or remission. Periods of improvement can last days, months, and even years among patients. Early symptoms of the disease are usually vague and nonspecific. Multiple lab tests must be performed overtime before an accurate diagnosis can be made.

American College of Rheumatology's criteria for diagnosing Systemic Lupus Erythematosus include:

  • Butterfly-shaped rash over the cheeks
  • Sores in the mouth
  • Rash appearing areas exposed to the sun
  • Arthritis involving one or more joints
  • Inflammation of the Kidneys
  • Nervous systems disorders such as seizures, mental disorders, and strokes
  • Fevers
  • Weight loss
  • Hair loss
  • Poor circulation in the fingers and toes
Treatment varies among patients depending on the condition and whether the disease is active or inactive. Regular medical evalutions are important to monitor the disease and appropriate treatment is available depending on the particular problems the patient has. For mild inflammation in the joints, non-steroidal anti-inflammatory (NSAIDs) drugs are recommended. Patients suffering from Systemic Lupus Erythematosus also use other medications such as corticosteroids. It is important to protect the bones when any steroids are used. Many choose alternative therapies, which include meditation and relaxation, exercise, acupuncture, and natural supplements, such as Glucosamine and Chondroitin sulfate. Talk to your physician or Rheumatologist about your specific symptoms before seeking any treatment.
 


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