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Erythrocyte Sedimentation Rate (ESR), Frequently Ordered Test

The Erythrocyte Sedimentation Rate (ESR) is a screening test for various diseases. It is a simple one-hour test that is frequently ordered in clinical medicine. An Erythrocyte Sedimentation Rate measures the distance that erythrocytes have fallen after one hour in a vertical column of anticoagulant blood under the influence of gravity.

Women tend to have a higher Erythrocyte Sedimentation Rate values, as do the elderly. This test is used to monitor inflammatory or malignant diseases. The amount of fibrinogen present in the blood directly correlates with the Erythrocyte Sedimentation Rate. Any condition that elevates levels of fibrinogen may also elevate the erythrocyte sedimentation rate.

Conditions that elevate fibrinogen include:

  • Rheumatoid arthritis
  • Rheumatic fever
  • Pregnancy
  • Diabetes Mellitus
  • End-stage renal failure
  • Heart disease
  • Collagen vascular disease
  • Malignancy
Lower-than-normal levels occur with:
  • Congestive heart failure
  • Hyperviscosity
  • Hypofibrinogenemia (decrease fibrinogen levels)
  • Low plasma protein
  • Sickle cell anemia
The erythrocyte sedimentation rate has been shown to satisfactory monitor acute-phase response to diseases after the first 24 hours; however, usefulness of this test has decreased as new and more accurate methods of evaluating diseases have been developed.


Symptoms of Arthritis | Osteoarthritis | Rheumatoid Arthritis | Gout (Gouty Arthritis) | Juvenile Rheumatoid Arthritis | Systemic Lupus Erythematosus | Synovial Joints | C-reactive Protein | Rheumatoid Factor | Antinuclear Antibody (ANA) | Uric Acid Test | Fibrinogen | Erythrocyte Sedimentation Rate (ESR) | Arthritis Diet | Glucosamine and Chondroitin sulfate | Rheumatoid Arthritis and Potassium | Resources | Arthritin | Omegacin+| Buffer-pH+ | pH Test Strips



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